Modulating solvation interactions of deep eutectic solvents formed by ammonium salts and carboxylic acids through varying the molar ratio of hydrogen bond donor and acceptor

• Measurement of solvation interactions for deep eutectic solvents (DESs) is discussed. DES power varies with hydrogen bond acceptor (HBA)/hydrogen donor (HBD) ratio. Inverse gas chromatography sensitive to measure small variations in HBA/HBD Eighteen mixtures varied HBA and HBD composition are examined. Hydrogen basicity impacted the most when ratio varied. Deep have gained increasing popularity separation science due fact that their physico-chemical properties can be easily fine-tuned by varying type or (HBA) (HBD). While it well-known molar affects melting point a mixture, much less understood regarding its effect on magnitude individual interactions. This largely established solvatochromic dye methods lack sensitivity slightly mixture. Herein, this study first variation changes using inverse (IGC). Solute-solvent three different systems comprised ammonium salts organic acids were The probe molecules studied 18 composition. basicity, acidity, dispersive-type exhibited greatest change was Results from demonstrate used modulate characteristics class DESs separations stoichiometric important ensuring reproducible preparation.